A cell therapy is a type of treatment consisting of cells, which are administered to a patient to improve the status of a disease. In recent years, multiple cell therapies have been approved to treat different diseases, such as certain blood cancers.
However, to date, no cell therapy has been approved to treat critical limb ischemia.
Cell therapies are prepared from living human cells, which can be obtained from the patient (as is the case for REX-001, which is being investigated in this study), or from a donor. Many different cell types exist, with different functions in the body, and some could play an important role in treating certain diseases. Depending on the type of disease, specific cell types are collected to prepare the cell therapy. In general, the collected cells will be processed in a laboratory after collection, before they are used to treat a patient.